SYNTHESIS OF NOVEL URSOLIC ACID DERIVATIVES
نویسندگان
چکیده
منابع مشابه
Synthesis and in vitro cytotoxicity of novel ursolic acid derivatives.
In an effort to improve potential hepatoprotective and anti-tumor activities, eight novel ursolic acid (UA) derivatives were designed and synthesized with substitution at positions of C-3, C-11 and C-28 of UA. Their structures were confirmed using IR, MS and (1)H-NMR and elemental analysis. Their in vitro cytotoxicity against various cancer cell lines (HeLa, SKOV3 and BGC-823) was evaluated by ...
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Ursolic acid (UA) is a naturally bioactive compound that possesses potential anti-diabetic activity. The relatively safe and effective molecule intrigued us to further explore and to improve its anti-diabetic activity. In the present study, a series of novel UA analogues was synthesized and their structures were characterized. Their bioactivities against the α-glucosidase from baker's yeast wer...
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ژورنال
عنوان ژورنال: Science and Technology Development Journal
سال: 2011
ISSN: 1859-0128
DOI: 10.32508/stdj.v14i3.1963